As Disintegrating agent: Kyron T has a very high swelling tendency of hydration either in contact with water or G.I. fluids causing fast disintegration without. Article | The purpose of present study was to compare Kyron T with other superdisintegrants and optimize the fast dissolving tablet of. industry to mask the taste of bitter medicine to achieve stability and drugs. It is white to off white fine powder, swellable in water. KYRON T is derived from.
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FTIR spectrum of physical and co-processed mixture of polymer and their comparisons with drug. Keep away from moisture.
Kyron T – View Specifications & Details by Corel Pharma Chem, Ahmedabad | ID:
Formulation F-X was emerged as the overall best formulation based on drug release characteristics in pH 6. Besides, our company is proficient enough to provide effective solutions to various industry’s specific problems and needs. Erick Legrand Expert opinion on pharmacotherapy The contents of kyrln beaker ml capacity were stirred on a magnetic stirrer.
Subscribe to our Newsletter All our latest content delivered to your inbox. Powder was poured through the funnel until the apex of the conical pile touched the tip of the funnel. User Username Password Remember me. WaghSapna S.
Export Data and Price of kyron t | Zauba
The dried granules were sifted on sieve and stored in air tight container till further use [ 10 ]. The standardized formulation F-X was compared with commercial conventional marketed tablets for percentage metoclopramide hydrochloride dissolved. It is a very high purity polymer used in pharmaceutical formulations as a super fast disintegrant as well as dissolution improver in solid dosage forms like tablets, capsules, pellets etc.
The objective of co-processing is to provide the synergy of functionality improvement as well as to provide an excipient with multiple characteristics build into them [ 6 ].
Furthermore, our wide distribution network in around 15 countries enable us to supply the products in more than 35 countries. All the ingredients except granular directly compressible excipient were passed through sieve separately. At intervals of 1 month, the tablets were visually examined for any physical changes and evaluated for in vitro drug release studies [ 16 ].
The simple physical blends and co-processed mixture of superdisintegrants were characterized for angle of repose, bulk density, tapped density, Carr’s index, Hausner’s ratio and compatibility studies by FTIR spectroscopy. Co-processed excipients exhibited improved functionality as compared to their physical mixtures [ 7 ]. The co-processed superdisintegrants were evaluated for their flow and compression properties in comparison with physical mixture of superdisintegrants.
Evaluation of KYRON T-314 ( Polacrillin Potassium ) as a novel super disintegrant
The thickness of the prepared tablets was found to be in the range of 3. Skip to search form Skip to main content.
Formulation and optimization of mouth dissolve tablets containing rofecoxib solid dispersion Omaima A. Formulation of a fast-dissolving ketoprofen tablet using freeze-drying in blisters technique. Author’s work Hide Show all. Stability study was conducted as per ICH guidelines. Department of Pharmaceutics, K. Presently, our organization has become one of the prominent engineering group who has all the modern facilities for designing, developing and manufacturing defect free range of Polymers to the clients.
This indicates that the drug release process is first order in nature. View Contact Call Seller Now. The cumulative percent drug released from formulation F-X was compared with the tablets obtained from conventional method of manufacture as well as with commercial conventional formulation CCF figs.
Get Best Price Request a quote. AminRuchi AgrawalRikita K. Required quantity is from 2. Related Items Author’s work. Granulation procedure Tablet Dosage Form. The authors thank the Lincoln Pharmaceuticals Limited, Ahmedabad for providing gift samples of metoclopramide hydrochloride, crospovidone, polyvinylpyrrolidone and mannitol. A piece of tissue paper folded twice was placed in a small petridish i.
S Mundada Department of Pharmaceutics, S.
Thus coprocessing of two superdisintegrants with wicking and swelling properties leads to the rapid disintegration of tablets in contact with saliva within few seconds and also serves as a multifunctional excipient [ 9 ].
All the tablet formulations were evaluated for flow property and compression characteristics. The flow properties were graded as per the USP specifications [ 15 ]. The composition of tablet is presented in Table 2. Disintegration time t-3144 of much importance in formulation of melt-inmouth tablets oyron was found to be in the range of 5.